PhD Project in neuronal transcription factor biophysics

This PhD project in neuronal transcription factor biophysics requires a strong foundation in molecular and cellular biology, with a specific focus on transcription factors involved in neuronal function. Candidates should possess a solid understanding of biophysical principles as applied to protein-DNA interactions, including techniques such as electrophoretic mobility shift assays, chromatin immunoprecipitation, fluorescence microscopy, and possibly single-molecule biophysics methods. Experience or familiarity with molecular cloning, protein expression and purification, and biochemical assays is advantageous. The role demands analytical skills to interpret complex biological data and possibly computational skills for modeling transcription factor dynamics. A background in neuroscience or neurobiology is beneficial to contextualize the transcription factors' role in neuronal systems. Given the academic nature of the project, candidates are expected to have strong research skills, including literature review, experimental design, and scientific communication. The position is suitable for candidates with a bachelor's or master's degree in biochemistry, molecular biology, biophysics, neuroscience, or related fields, aiming to develop expertise in the intersection of neurobiology and biophysics. Overall, the project emphasizes interdisciplinary competence in biological sciences and quantitative biophysical methods to understand transcriptional regulation in neurons.